Clinical Outcome Assessment (COA) Solutions

Access COA expertise, licensing, eCOA migration, and translation automation to improve the patient and healthcare provider experience.

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End-to-End COA Solutions: Speed Time-to-Market, Mitigate Risk, and Ensure Global Regulatory Compliance

Enable superior patient data quality with AI-powered eCOA migration, licensing, data collection and expert support across a variety of therapeutic areas. Sponsors and eCOA providers trust TransPerfect to improve ease, speed, compliance, and quality of patient data reporting—all while minimizing the risk of error. Navigate the complexity of COA management with the next generation of clinical data integrity and patient safety.

    Translation and COA Linguistic Validation

    License, translate, and adapt COAs across a variety of therapeutic areas, while improving data quality. Translate and validate patient-reported outcomes (PROs), clinician-reported outcomes (ClinROs), observer-reported outcomes (ObsROs), and performance outcomes (PerfOs). Our specialists follow the latest guidelines and ISPOR Good Practice recommendations to deliver compliant and culturally appropriate COA translations in complex regulatory environments such as the United States, Japan, China, and the European Union.

    Licensing and Copyright Support

    Simplify the licensing and copyright process for scales, instruments, and patient questionnaires by leveraging our long-standing relationships with copyright holders, authors, and developers. This enables your team to secure necessary permissions efficiently, accelerating project timelines.

    COA Library and Document Management

    Store all COA content (PRO, ClinRO, ObsRO, PerfO) in a secure, centralized cloud repository, including development records, qualification submissions, licensing/copyright details, validation reports, and eCOA documentation. Your team can easily track and manage all project activities—formatting, translation, and eCOA tasks—ensuring smooth, organized workflows.

    GlobalLink XCompare™ for eCOA Migration

    Streamline your eCOA migration process with an industry-leading eCOA platform that improves the ease, speed, compliance, and quality of patient data reporting. GlobalLink XCompare is our proprietary risk-mitigating technology used during the migration of validated paper COAs to electronic platforms. We provide migration assessment, eCOA adaptation and migration, screenshot review and certification, and post-localization device testing. Sponsors and eCOA providers trust XCompare to avoid common migration issues, reduce errors by 97%, and accelerate migration timelines by 50%.

    GlobalLink Strings for Screenshot Review

    Remove the need for passing technical files back and forth and rounds of review. GlobalLink Strings connects directly to the ePRO/eCOA app via API. TransPerfect specialists manage the full testing process and remove the electronic patient reported outcomes (ePRO) vendor, which allows for 2.5 times faster turnaround time and reduced project management.

    Rater Training Support

    Provide a comprehensive suite of solutions to support rater training efforts. We offer creation, translation, and adaptation of all training materials, including those delivered by video and through interactive e-learning courses. Our subject matter experts support ensuring compliance to validated scales for greater scoring excellence. TransPerfect has over 1,200 clinician reviewers in our network to review any Clinician-Reported Outcomes (ClinRO) work across any CNS therapeutic area.

    Patient Interviews

    Support patient-centered outcomes for clinical research, including the execution of patient interviews throughout the life cycle of the clinical study. As a trusted partner to CROs and sponsors, TransPerfect offers a comprehensive range of interview services to develop and validate COAs, including concept elicitation, patient experience, and exit interviews. Each collaboration includes a thorough review of the sponsor’s goals to ensure qualified interviewers are trained on the study-specific requirements. We keep your study on track with timely delivery of interview transcripts, translations, adverse event reports, and feedback reports.

    Upholding the Highest Industry Standards to Ensure Conceptual Equivalence and Cultural Appropriateness

    Protect Patient Safety

    All TransPerfect COA Division production staff complete regular Good Clinical Practice (GCP) training. Our clients also have access to ongoing training on the most up-to-date industry standards for COA translation.

    Accurately Capture Patient Data

    As the first major language services provider to be ISO 9001, ISO 17100, and EN certified, TransPerfect undergoes regular audits for quality assurance. Our linguistic validation team has extensive knowledge of FDA, EMA, PMDA, MHRA, and ISPOR Guidance documents.

    Comply with Global Regulatory Requirements

    TransPerfect’s 21 CFR Part 11 compliant Trial Interactive online document repository enables web-based archiving of COAs for easy access and retrieval. Centralize clinical outcome assessments and eCOA documentation with the platform named “Best Technology for Sponsors.”

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    A Checklist for eCOA Solutions Deployment

    Selecting and deploying a new eCOA solution involves many important factors - from determining the capabilities of the Language Service Provider (LSP) to identifying the technology used for each COA migration - and it’s impossible not to worry about missing a key detail in the process.

    Download our checklist to learn about the eCOA landscape.

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    Trusted COA Solutions for Clinical Trial Success

    Discover how TransPerfect streamlines COA management and translation.

    • Video

      What Is TransPerfect's COA Solution?

    • Video

      Why Was TransPerfect's COA Solution Created?

    • Video

      What Are the Main Challenges TransPerfect's COA Solution Solves?

    • Video

      What Are the Main Benefits of Our COA Solution?

    • Video

      Who Does TransPerfect's COA Solution Help?

    • Video

      Why Do Clients Love TransPerfect's COA Solution?

    • Video

      Why Should Clients Choose TransPerfect's COA Solution?

    The Future of eCOA and Wearable Devices

    Electronic Clinical Outcome Assessment (eCOA) wearables support the collection of large volumes of patient-reported data. Discover how these devices can improve data collection and integrity. This blog explores the future of wearable sensors—and the advantages they provide over traditional COA data collection methods.

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    Innovation in Clinical Outcome Assessment Solutions by the Numbers

    97 %

    Risk mitigation during eCOA migration

    50 %

    Faster review cycles with XCompare

    2.5 x

    Faster turnaround times by eliminating ePRO vendor

    100 %

    Compliance with copyright holders for legal requirements

    24/7

    365 days of the year access

    Ensure Conceptual Equivalence and Cultural Appropriateness in COAs Across a Variety of Therapeutic Areas

    • Aesthetic Medicine
    • Cardiology
    • CNS/Neurology/Psychiatry
    • Congenital/Hereditary Diseases
    • Dermatology
    • Endocrinology
    • Gastroenterology
    • Genetic Disease
    • Healthy Volunteers
    • Hemic/Lymphatic
    • Hepatology
    • Immunology
    • Infectious Diseases
    • Musculoskeletal
    • Nephrology
    • Neurology
    • Obstetrics/Gynecology
    • Oncology
    • Ophthalmology
    • Otolaryngology
    • Otorhinolaryngology
    • Orthopedics
    • Pediatrics
    • Pain
    • Plastic Surgery
    • Psychiatry/Psychology
    • Respiratory
    • Rheumatology
    • Sexual Functioning
    • Sleep Disorders
    • Spondylitis
    • Trauma
    • Urology
    • Vaccines

    Certifications and Memberships

    TransPerfect is an active participant in the outcomes research and health economics world and has a strong record of academic achievement and participation.

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    C-Path Institute

    News and Thought Leadership

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    Accelerating Pharma Labeling with Intelligent, Compliant Content
    Blog

    Health Canada's Transition to XML: What Regulatory Teams Need to Know

    In a continued push toward modernization and transparency, Health Canada has entered the next phase of its digital transformation with a mandate requiring the use of advanced extensible markup language product monograph (XML PM) files. This change builds on earlier...
    Webinar

    LifeSci Talks COA Series | Balancing Innovation and Integrity: AI’s Place in Patient-Focused Research

    Artificial intelligence is redefining what’s possible across the clinical development lifecycle, but with rapid innovation comes the need for thoughtful oversight. In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with ...
    White Paper

    Web Localization Playbook for Life Sciences

    The life sciences industry relies on websites to connect with patients, sites, and global audiences. Whether you're launching a patient recruitment campaign or managing an international healthcare marketing initiative, localization ensures your message is not just understood ...
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    Rewriting the Rules of Informed Consent Development with AI

    Regardless of the market a clinical trial is being conducted in, getting locally approved informed consent forms (ICFs) consume as much as 12% of a clinical trial budget before it even begins. Each ICF must be clear and delicately balance local regulations and patient ...
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    OpTImize London

    - | Park Plaza London Westminster Bridge 200 Westminster Bridge Road London, England, United Kingdom, SE17UT ...
    Webinar

    LifeSci Talks COA Series | Making the Most of Smaller Population Samples: Qualitative Insights in Rare Disease

    In this episode of LifeSci Talks, Mark Wade, Global Practice Leader at TransPerfect Life Sciences, sits down with Dr. Kate Williams, Director of Patient-Centred Outcomes Research at Acaster Lloyd, to explore the nuances of gathering and applying qualitative data in rare disease ...

    Are you launching a study in the next 6-12 months?

    Now is the right time to engage with us. We can help you plan licensing, get ahead of linguistic validation, and align key study milestones to keep timelines on track. Talk with our experts to get your study off the ground with speed, accuracy, and regulatory compliance—right from the start.

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